The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are ...
Cat # 15996614
100 µL
Cat # 13259788
100 µL
Cat # 15953185
100 µL
Cat # 16187454
100 ug
Cat # 15536832
100 µL
Cat # 13480996
100 ug
Cat # 16663295
100 µL
Cat # 15767534
25 ug
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